Traut, R.R.,
Dey, D., Bochkariov, D.E., Oleinikov, A.V., Jokhadze, G.G., Hamman, B.,
Jameson, D. (1995) “Location and Domain Structure of Escherichia coli Ribosomal Protein L7/L12: Site Specific Cysteine
Cross-Linking and Attachment of Fluorescent Probes”. Biochem. Cell Biol. 73, 949-958.
Johnson,
A.E., Liao, S., Lin, J., Hamman, B., Do, H., Cowie, A., and Andrews,
D.W. (1995) “The Environment of Nascent
Secretory and Membrane Proteins at the Endoplasmic Reticulum Membrane during
Translocation and Integration”. Cold Spring Harb. Symp. Quant. Biol. 60, 71-82.
Hamman, B.D.,
Oleinikov, A.V., Jokhadze, G.G., Bochkariov, D.E., Traut, R.R. and. Jameson,
D.M. (1996) “Tetramethylrhodamine Dimer Formation as a Spectroscopic Probe of
the Conformation of Escherichia coli Ribosomal
Protein L7/L12 Dimers” J. Biol. Chem. 271,
7568-7573.
Hamman, B.D.,
Oleinikov, A.V., Jokhadze, G.G., Traut, R.R., and Jameson, D.M. (1996)
“Rotational and Conformational Dynamics of Escherichia
coli Ribosomal Protein L7/L12” Biochemistry
35,
16672-16679.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Traut, R.R., and Jameson, D.M. (1996) “Dimer/ Monomer Equilibrium and Domain Separations of
Escherichia
coli Ribosomal Protein L7/L12” Biochemistry
35,
16680-16686.
Hamman, B.D., Chen, J.-C., Johnson, E.E., and Johnson, A.E. (1997) “The Aqueous Pore through the Translocon Has a Diameter of 40-60 Å during
Cotranslational
Protein Translocation at the ER Membrane”
Cell 89,
535-544.
Hamman, B.D.,
Hendershot, L.M., and Johnson, A.E. (1998) “BiP Maintains the Permeability
Barrier of the ER Membrane by Sealing the Lumenal End of the Translocon Pore
before and Early in Protein
Translocation” Cell 92,
747-758.
Shepard, L.A.,
Heuck, A.P., Hamman, B.D., Rossjohn, J., Parker, M.W., Ryan, K.R.,
Johnson, A.E., and Tweten, R.K. (1999)
“Identification of a Membrane-Spanning Domain of the Thiol-Activated
Pore-Forming Toxin Clostridium
perfringens Perfringolysin O: An a-Helical to b-Sheet
Transition Identified by Fluorescence Spectroscopy”. Biochemistry 37, 14563-14574.
Mere, L.,
Bennett, T., Coassin, P., England, P., Hamman, B., Rink, T., Zimmerman,
S., and Negelescu, P. (1999) "Miniaturized FRET Assays and Microfluidics: Key Components for Ultra-High-Throughput
Screening” Drug Discovery Today 4, 363-369.
Hamman, B.D.*,
Pollok, B.S., Bennett, T., Allen, J., and Heim, R. (2002) "Binding of a Pleckstrin Homology Domain Protein to
Phosphoinositide in Membranes: A Miniaturized FRET-Based Assay for Drug
Screening" J. Biomol. Screen. 7, 49-59. *Also senior author.
Rodems, S.M.*, Hamman,
B.D.*, Lin C., Zhao, J., Shah, S., Heidary, D., Makings, L., Stack, J.H.,
and Pollok, B.A. (2002) “A FRET-Based In
Vitro Assay for both Tyrosine- and Serine/Threonine-Specific Kinases and
Phosphatases”. Assay Drug Dev. Tech. 1, 9-20. *Contributed equally.
Patents
Pollok,
B.A.*, Hamman, B.D.*, Rodems, S., Makings, L. “Optical Probes and
Assays”. Patent # US 6,410,255 B1 issued on June 25th, 2002 with 31 claims
accepted. *Primary intellectual
contributors.
Hamman,
B.D.*, Heim, R., Pollok B.A., Allen, J.
“Methods for screening interactions between two compounds using
fluorescence resonance energy transfer phenomenon and kits for performing said
screening methods”. Application under review. *Primary intellectual
contributor.
Grants
Hamman, B.D.*, Clark, H., Heim, R., Pollok, B.A., and Lin, Y.-Z. “MTS in Drug Discovery”. NIH SBIR grant. Received $132,000 for one year (01/00-01/01). *Principal Investigator.
Published Abstracts and Posters: 27 (available on request)
Invited Seminars and Interviews
Department of Biological Chemistry, University of
California, Davis (August, 1992)
Department of Biochemistry and Biophysics, University of
Hawaii, Honolulu (April, 1993)
Department of Biological Chemistry, University of
California, Davis (August, 1994)
Department of Biochemistry and Biophysics, Texas A&M
University, College Station (April, 1995)
Helios Pharmaceuticals, Louisville, Kentucky (September,
1997)
Department of
Biochemistry and Molecular Biology, University of Miami School of Medicine,
Florida (January, 1998)
Department of Biochemistry, North Carolina State University,
Raleigh (February, 1998)
Department of Biological Sciences, Rutgers University,
Newark, New Jersey (February, 1998)
Aurora Biosciences Corporation, San Diego, California
(February, 1998)
Department of Chemistry and Biochemistry, San Francisco
State University (March, 1998)
Department of Biochemistry, University of Toronto, Canada
(March, 1998)
Department of
Cell and Developmental Biology, University of Pennsylvania, Philadelphia
(March, 1998)
Department of
Biochemistry and Molecular Biology, Notre Dame University, South Bend, Indiana
(March, 1998)
Department of Biology, Western University Health Science
Center, Pomona, CA (March, 1998)
Aurora
Biosciences Corporation (1998-2003) Presented at 8 different Technology Focus
Meetings and gave a course to Pfizer involving an overview of
fluorescence-based assay technologies.
Also spoke at 2001 Aurora Symposium on PH Domains as Drug Discovery
Targets.
Panvera
Corporation, Madison, Wisconsin (June, 2001), Overview on Novel Fluorescence
Technologies at Aurora.
Anadys
Pharmaceuticals, Inc., San Diego, California (February, 2002)
Replidyne
Pharmaceuticals, Inc., Louisville, Colorado (September, 2003)
ISIS
Pharmaceuticals, Inc., Carlsbad, California (September, 2003)
Lexicon Genetics,
Inc., The Woodlands, Texas (January, 2004)