Appiah K.K., Kostich W.A., Gerritz S.W., Huang Y., Hamman B.D., Allen J., Zhang W., Lanthorn T.H., Albright C.F., Westphal R., Banks M.N., and O'Connell J.C. (2011) “A High-throughput Screen for Receptor Protein Tyrosine Phosphatase-gamma Selective Inhibitors.” J. Biomol. Screen. 16(5), 476-485.
Revelli J.P., Smith D., Allen J., Jeter-Jones S., Shadoan M.K., Desai U., Schneider M., van Sligtenhorst I., Kirkpatrick L., Platt K.A., Suwanichkul A., Savelieva K., Gerhardt B., Mitchell J., Syrewicz J., Zambrowicz B., Hamman B.D., Vogel P., and Powell D.R. (2011) “Profound Obesity Secondary to Hyperphagia in Mice Lacking Kinase Suppressor of Ras 2.” Obesity 19(5), 1010-1018.
Harrison B.A., Whitlock N.A., Voronkov M.V., Almstead Z.Y., Gu K.J., Mabon R., Gardyan M., Hamman B.D., Allen J., Gopinathan S., McKnight B., Crist M., Zhang Y., Liu Y., Courtney L.F., Key B., Zhou J., Patel N., Yates P.W., Liu Q., Wilson A.G., Kimball S.D., Crosson C.E., Rice D.S., and Rawlins D.B. (2009) “Novel class of LIM-kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma.” J. Med Chem. 52(21), 6515-6518.
Hu L.A., Zhou T., Hamman B.D., and Liu Q. (2008) “A Homogeneous G Protein-coupled Receptor Ligand Binding Assay Based on Time-resolved Fluorescence Resonance Energy Transfer.” Assay Drug Dev. Technol. 6(4), 543-550.
Rodems, S.M.*, Hamman, B.D.*, Lin C., Zhao, J., Shah, S., Heidary, D., Makings, L., Stack, J.H., and Pollok, B.A. (2002) “A FRET-Based In Vitro Assay for both Tyrosine- and Serine/Threonine-Specific Kinases and Phosphatases.” Assay Drug Dev. Technol. 1, 9-20. Described the Z’-Lyte assay technology currently sold by Invitrogen.
Hamman, B.D.*, Pollok, B.S., Bennett, T., Allen, J., and Heim, R. (2002) "Binding of a Pleckstrin Homology Domain Protein to Phosphoinositide in Membranes: A Miniaturized FRET-Based Assay for Drug Screening." J. Biomol. Screen. 7, 49-59. *Also senior author.
Mere, L., Bennett, T., Coassin, P., England, P., Hamman, B., Rink, T., Zimmerman, S., and Negelescu, P. (1999) "Miniaturized FRET Assays and Microfluidics: Key Components for Ultra-High-Throughput Screening.” Drug Discovery Today 4, 363-369.
Shepard, L.A., Heuck, A.P., Hamman, B.D., Rossjohn, J., Parker, M.W., Ryan, K.R., Johnson, A.E., and Tweten, R.K. (1999) “Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming Toxin Clostridium perfringens Perfringolysin O: An a-Helical to b-Sheet Transition Identified by Fluorescence Spectroscopy.” Biochemistry 37, 14563-14574.
Hamman, B.D., Hendershot, L.M., and Johnson, A.E. (1998) “BiP Maintains the Permeability Barrier of the ER Membrane by Sealing the Lumenal End of the Translocon Pore before and Early in Protein Translocation.” Cell 92, 747-758. Cited 347 times as of 4-Feb-2012.
Membrane.” Cell 89, 535-544. Cited 244 times as of 4-Feb-2012.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Traut, R.R., and Jameson, D.M. (1996) “Dimer/ Monomer Equilibrium and Domain Separations of Escherichia coli Ribosomal Protein L7/L12.” Biochemistry 35, 16680-16686.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Traut, R.R., and Jameson, D.M. (1996) “Rotational and Conformational Dynamics of Escherichia coli Ribosomal Protein L7/L12.” Biochemistry 35, 16672-16679.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Bochkariov, D.E., Traut, R.R. and. Jameson, D.M. (1996) “Tetramethylrhodamine Dimer Formation as a Spectroscopic Probe of the Conformation of Escherichia coli Ribosomal Protein L7/L12 Dimers.” J. Biol. Chem. 271, 7568-7573.
Johnson, A.E., Liao, S., Lin, J., Hamman, B., Do, H., Cowie, A., and Andrews, D.W. (1995) “The Environment of Nascent Secretory and Membrane Proteins at the Endoplasmic Reticulum Membrane during Translocation and Integration.” Cold Spring Harb. Symp. Quant. Biol. 60, 71-82.
Traut, R.R., Dey, D., Bochkariov, D.E., Oleinikov, A.V., Jokhadze, G.G., Hamman, B., Jameson, D. (1995) “Location and Domain Structure of Escherichia coli Ribosomal Protein L7/L12: Site Specific Cysteine Cross-Linking and Attachment of Fluorescent Probes.” Biochem. Cell Biol. 73, 949-958.
Patents
Pollok, B.A.*, Hamman, B.D.*, Rodems, S., Makings, L. “Optical Probes and Assays.” Patent # US 6,410,255 B1 issued on June 25th, 2002 with 31 claims accepted.
Grants
Hamman, B.D.*, Clark, H., Heim, R., Pollok, B.A., and Lin, Y.-Z. “MTS in Drug Discovery.” NIH SBIR grant. Received $132,000 for one year (01/00-01/01). *Principal Investigator.