Traut, R.R., Dey, D., Bochkariov, D.E., Oleinikov, A.V., Jokhadze, G.G., Hamman, B., Jameson, D. (1995) “Location and Domain Structure of Escherichia coli Ribosomal Protein L7/L12: Site Specific Cysteine Cross-Linking and Attachment of Fluorescent Probes”. Biochem. Cell Biol. 73, 949-958.
Johnson, A.E., Liao, S., Lin, J., Hamman, B., Do, H., Cowie, A., and Andrews, D.W. (1995) “The Environment of Nascent Secretory and Membrane Proteins at the Endoplasmic Reticulum Membrane during Translocation and Integration”. Cold Spring Harb. Symp. Quant. Biol. 60, 71-82.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Bochkariov, D.E., Traut, R.R. and. Jameson, D.M. (1996) “Tetramethylrhodamine Dimer Formation as a Spectroscopic Probe of the Conformation of Escherichia coli Ribosomal Protein L7/L12 Dimers” J. Biol. Chem. 271, 7568-7573.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Traut, R.R., and Jameson, D.M. (1996) “Rotational and Conformational Dynamics of Escherichia coli Ribosomal Protein L7/L12” Biochemistry 35, 16672-16679.
Hamman, B.D., Oleinikov, A.V., Jokhadze, G.G., Traut, R.R., and Jameson, D.M. (1996) “Dimer/ Monomer Equilibrium and Domain Separations of
Escherichia coli Ribosomal Protein L7/L12” Biochemistry 35, 16680-16686.
Hamman, B.D., Chen, J.-C., Johnson, E.E., and Johnson, A.E. (1997) “The Aqueous Pore through the Translocon Has a Diameter of 40-60 Å during
Cotranslational Protein Translocation at the ER Membrane” Cell 89, 535-544.
Hamman, B.D., Hendershot, L.M., and Johnson, A.E. (1998) “BiP Maintains the Permeability Barrier of the ER Membrane by Sealing the Lumenal End of the Translocon Pore before and Early in Protein Translocation” Cell 92, 747-758.
Shepard, L.A., Heuck, A.P., Hamman, B.D., Rossjohn, J., Parker, M.W., Ryan, K.R., Johnson, A.E., and Tweten, R.K. (1999) “Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming Toxin Clostridium perfringens Perfringolysin O: An a-Helical to b-Sheet Transition Identified by Fluorescence Spectroscopy”. Biochemistry 37, 14563-14574.
Mere, L., Bennett, T., Coassin, P., England, P., Hamman, B., Rink, T., Zimmerman, S., and Negelescu, P. (1999) "Miniaturized FRET Assays and Microfluidics: Key Components for Ultra-High-Throughput Screening” Drug Discovery Today 4, 363-369.
Hamman, B.D.*, Pollok, B.S., Bennett, T., Allen, J., and Heim, R. (2002) "Binding of a Pleckstrin Homology Domain Protein to Phosphoinositide in Membranes: A Miniaturized FRET-Based Assay for Drug Screening" J. Biomol. Screen. 7, 49-59. *Also senior author.
Rodems, S.M.*, Hamman, B.D.*, Lin C., Zhao, J., Shah, S., Heidary, D., Makings, L., Stack, J.H., and Pollok, B.A. (2002) “A FRET-Based In Vitro Assay for both Tyrosine- and Serine/Threonine-Specific Kinases and Phosphatases”. Assay Drug Dev. Tech. 1, 9-20. *Contributed equally.
Patents
Pollok, B.A.*, Hamman, B.D.*, Rodems, S., Makings, L. “Optical Probes and Assays”. Patent # US 6,410,255 B1 issued on June 25th, 2002 with 31 claims accepted. *Primary intellectual contributors.
Hamman, B.D.*, Heim, R., Pollok B.A., Allen, J. “Methods for screening interactions between two compounds using fluorescence resonance energy transfer phenomenon and kits for performing said screening methods”. Application under review. *Primary intellectual contributor.
Grants
Hamman, B.D.*, Clark, H., Heim, R., Pollok, B.A., and Lin, Y.-Z. “MTS in Drug Discovery”. NIH SBIR grant. Received $132,000 for one year (01/00-01/01). *Principal Investigator.
Published Abstracts and Posters: 27 (available on request)
Invited Seminars and Interviews
Department of Biological Chemistry, University of California, Davis (August, 1992)
Department of Biochemistry and Biophysics, University of Hawaii, Honolulu (April, 1993)
Department of Biological Chemistry, University of California, Davis (August, 1994)
Department of Biochemistry and Biophysics, Texas A&M University, College Station (April, 1995)
Helios Pharmaceuticals, Louisville, Kentucky (September, 1997)
Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, Florida (January, 1998)
Department of Biochemistry, North Carolina State University, Raleigh (February, 1998)
Department of Biological Sciences, Rutgers University, Newark, New Jersey (February, 1998)
Aurora Biosciences Corporation, San Diego, California (February, 1998)
Department of Chemistry and Biochemistry, San Francisco State University (March, 1998)
Department of Biochemistry, University of Toronto, Canada (March, 1998)
Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia (March, 1998)
Department of Biochemistry and Molecular Biology, Notre Dame University, South Bend, Indiana (March, 1998)
Department of Biology, Western University Health Science Center, Pomona, CA (March, 1998)
Aurora Biosciences Corporation (1998-2003) Presented at 8 different Technology Focus Meetings and gave a course to Pfizer involving an overview of fluorescence-based assay technologies. Also spoke at 2001 Aurora Symposium on PH Domains as Drug Discovery Targets.
Panvera Corporation, Madison, Wisconsin (June, 2001), Overview on Novel Fluorescence Technologies at Aurora.
Anadys Pharmaceuticals, Inc., San Diego, California (February, 2002)
Replidyne Pharmaceuticals, Inc., Louisville, Colorado (September, 2003)
ISIS Pharmaceuticals, Inc., Carlsbad, California (September, 2003)
Lexicon Genetics, Inc., The Woodlands, Texas (January, 2004)